| Prime Minister | Mario Draghi | Independent |
| Minister of Foreign Affairs | Luigi Di Maio | Five Star Movement |
| Minister of the Interior | Luciana Lamorgese | Independent |
| Minister of Justice | Marta Cartabia | Independent |
| Minister of Defence | Lorenzo Guerini | Democratic Party |
| Minister of Economy and Finance | Daniele Franco | Independent |
| Minister of Economic Development | Giancarlo Giorgetti | League |
| Minister of Agricultural, Food and Forestry Policies | Stefano Patuanelli | Five Star Movement |
| Minister for Ecological Transition | Roberto Cingolani | Independent |
| Minister of Infrastructure and Transport | Enrico Giovannini | Independent |
| Minister of Labour and Social Policies | Andrea Orlando | Democratic Party |
| Minister of Public Education | Patrizio Bianchi | Independent |
| Minister of University and Research | Maria Cristina Messa | Independent |
| Minister of Culture | Dario Franceschini | Democratic Party |
| Minister of Health | Roberto Speranza | Article One |
| Minister for Parliamentary Relations | Federico D'Incà | Five Star Movement |
| Minister of Public Administration | Renato Brunetta | Forza Italia |
| Minister of Regional Affairs and Autonomies | Mariastella Gelmini | Forza Italia |
| Minister for the South and Territorial Cohesion | Mara Carfagna | Forza Italia |
| Minister for Equal Opportunities and Family | Elena Bonetti | Italia Viva |
| Minister for Youth Policies | Fabiana Dadone | Five Star Movement |
| Minister for Technological Innovation and Digital Transition | Vittorio Colao | Independent |
| Minister of Tourism | Massimo Garavaglia | League |
| Minister for Disabilities | Erika Stefani | League |
| Secretary of the Council of Ministers | Roberto Garofoli | Independent |
概要